Difference between revisions of "Main Page"

(Sub-tasks for PGx at Oslo University Hospital)
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
<strong>At the Farmakorakels Wiki we intend to prestent useful information about pharmacogenomics (PGx) for potential, future use at Oslo University Hospital.</strong>
 
<strong>At the Farmakorakels Wiki we intend to prestent useful information about pharmacogenomics (PGx) for potential, future use at Oslo University Hospital.</strong>
  
For information about the current state of pharmacogenomics at Oslo University Hospital, please check out http://www.anx.no.
+
For information about the current state of pharmacogenetics at Oslo University Hospital (in Norwegian), please check out http://www.anx.no.
  
 
==Systematic overview of current state of the PGx project==  
 
==Systematic overview of current state of the PGx project==  
[https://www.pgx.no/farmakorakel/Gjerald%20et%20al%20-%20Pipeline%20for%20knowledge%20curation%20and%20decision%20support%20in%20pharmacogenomics%20-%20ESHG.pdf Presentation at ESHG 2018]
+
[https://www.pgx.no/farmakorakel/Gjerald%20et%20al%20-%20Pipeline%20for%20knowledge%20curation%20and%20decision%20support%20in%20pharmacogenomics%20-%20ESHG.pdf Poster presentation at ESHG 2018]
  
 
==Sub-tasks for PGx at Oslo University Hospital==
 
==Sub-tasks for PGx at Oslo University Hospital==
*Making standardized PGx recommendations, using the Stanford's WebProtégé at https://www.pgx.no/webprotege
+
* Making standardized PGx recommendations, using a copy of the Stanford's WebProtégé, at https://www.pgx.no/webprotege
*Distribution of recommendations by the REST API [[Pharmacoracle]]
+
** [[WebProtege|Tutorial]] for curation of guidelines for pharmacogenomics
*Sorting out challenges in the [[Allele definition|definition of alleles]] and how to treat alleles with [[Unknown function]]
+
* Distribution of recommendations by the REST API [[Pharmacoracle]]
*Integrating PGx decision support in the hospital prescription module by using the openEHR framework
+
* Using [[NGS|Next generation sequencing (NGS) for detecting PGx alleles]]
 +
** Introducing the [[Pharmacotyper]] in our [[Bioinformatic pipeline|bioinformatic pipeline]]  
 +
* Sorting out challenges with genotyping
 +
** Finding correct [[Allele definition|definitions of alleles]]  
 +
** Evaluate alleles with [[Unknown function|unknown function]]
 +
** Estimate the effect of a variant on gene expression [[Gene function|effect of a variant on gene expression]]
 +
* Integrating PGx decision support in the hospital prescription module by using the [https://arketyper.no/ckm/ Norwegian openEHR framework]

Latest revision as of 11:26, 27 February 2019

At the Farmakorakels Wiki we intend to prestent useful information about pharmacogenomics (PGx) for potential, future use at Oslo University Hospital.

For information about the current state of pharmacogenetics at Oslo University Hospital (in Norwegian), please check out http://www.anx.no.

Systematic overview of current state of the PGx project

Poster presentation at ESHG 2018

Sub-tasks for PGx at Oslo University Hospital