Anonymous

Changes

Main Page

393 bytes added, 11:26, 27 February 2019
Sub-tasks for PGx at Oslo University Hospital
<strong>At the Farmakorakels Wiki we intend to prestent useful information about pharmacogenomics (PGx) for potential, future use at Oslo University Hospital.</strong>
For information about the current state of pharmacogenomics pharmacogenetics at Oslo University Hospital(in Norwegian), please check out http://www.anx.no.
==Systematic overview of current state of the PGx project==
==Sub-tasks for PGx at Oslo University Hospital==
*Making standardized PGx recommendations, using a copy of the Stanford's WebProtégé , at https://www.pgx.no/webprotege** [[WebProtege|Tutorial]] for curation of guidelines for pharmacogenomics*Distribution of recommendations by the REST API [[Pharmacoracle]]*Using [[NGS|Next generation sequencing (NGS) for detecting PGx alleles]]** Introducing the [[Pharmacotyper]] in our [[Bioinformatic pipeline|bioinformatic pipeline]]*Sorting out challenges in the with genotyping** Finding correct [[Allele definition|definition definitions of alleles]] and how to treat ** Evaluate alleles with [[Unknown function|unknown function]]** Estimate the effect of a variant on gene expression [[Gene function|effect of a variant on gene expression]]*Integrating PGx decision support in the hospital prescription module by using the [https://arketyper.no/ckm/ Norwegian openEHR framework]