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* PGx alleles that are classified with ''Normal function'' status by PharmGKB
* alleles with no variants (which are usually classified by PharmGKB)
In addition, especially at least in the world of SNP-arrays, the definition of ''Normal function'' alleles and ''Unknown function'' alleles are overlapping* Alleles that are '''not''' classified by PharmGKBhave ''Normal function''
In other words: the definitions ''Normal function'' and ''Unknown function'' are overlapping.
If we replace the ''Unknown function'' classification with ''Normal function'', dosing recommendations will have to be changed accordingly.