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Unknown function

87 bytes added, 12:08, 13 July 2018
Alleles with unknown biochemical function
==Alleles with unknown biochemical function==
''Unknown funtion'' means that the biochemical function of the allele is unknown or uncertain.
There are at least three four kind of alleles that have unknown biochemical function
* PGx alleles that are classified with ''Unknown function'' status by PharmGKB
* Alleles PGx alleles that are listed by PharmGKB, but has no functional status* Unknown alleles with variants that cause changes to the protein, but which are not classified by PharmGKB* Alleles Unknown alleles with variants that do not cause changes to the protein, and which are not classified by PharmGKB
The dosing recommendation for patients with unknown biochemical function on at least one chromatid, is to follow the normal medication advice. This means that normal medication is recommended, '''even if the sister-chromatid has ''No function'' or ''Increased function'''''.