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Unknown function

26 bytes removed, 08:14, 8 August 2018
Alleles with unknown biochemical function
* Unknown alleles with variants that do not cause changes to the protein, and which are not classified by PharmGKB
The There is no explicit dosing recommendation for patients with an unknown biochemical function allele on at least one chromatid, is to follow the normal medication advice. This means that there is no special medication recommendation '''even if the sister-chromatid has ''No function'' or ''Increased function'''''.
This dosing recommendation is very conservative, and the question is whether the allele with ''Unknown function'' should rather be treated as a ''Normal function'' allele (thereby assigning modified dosing recommendations to e.g. ''Unknown function''/''No function''-patients).